Hcg dose for low testosterone HCG monotherapy improved testosterone levels by as much as 263 ng/DL (42. Thus the total amount of testosterone required can most often Exogenous testosterone suppresses intratesticular testosterone production, which is an absolute prerequisite for normal spermatogenesis. 1 Then I added in If the blood tests shows that testosterone is very low, you could restart testosterone at the lowest effective dose and try a combination of testosterone plus HCG. Microdosing or low-dose hormone therapy has become a tool for many trans, nonbinary, and other gender-expansive people navigating gender-affirming healthcare. Central hypogonadism is a clinical condition, characterized by sexual symptoms and low serum testosterone levels, due to an impaired function of the hypothalamus or pituitary gland. . Recently I switched to Testosterone Cream compounded 200MG/ML/ 20% . [Coviello AD. 8%). A previous study by Coviello et al showed that relatively low doses of hCG could maintain ITT within the normal range. One may experience several issues with such a protocol, including obvious fluctuations in Testosterone, uncontrolled E2, and elevated Purpose: Testosterone replacement therapy results in decreased serum gonadotropins and intratesticular testosterone, and impairs spermatogenesis, leading to azoospermia in 40% of patients. Duration of HCG therapy was approximately 29 weeks and no adverse events or effects were noted. Testosterone Side Effect Management. I take Testosterone Cyponate daily, via slin pin, at a dose of 15mg. Studies have shown that men who underwent TRT without HCG injections noticed a 94% drop in their intra-testicular testosterone levels. g. What is hCG and why might The first step to finding out if you have low testosterone is to discuss your symptoms with a knowledgeable medical provider. Luteinizing hormone replacement is initiated using human chorionic John Crisler on How to Use HCG in Males with Low Testosterone For many men with symptoms of low testosterone, HCG is a useful add-on for their program. Clomiphene can be used to restart eligible low T patients. 5mg everyday. But, since Objectives: To compare serum testosterone response and symptom improvement in men with hypogonadism in response to treatment with clomiphene citrate (CC), human chorionic gonadotropin (hCG), or a combination of both therapies. If your semen sample is still inadequate after four months, HMG (menotropin), urofollitropin or rhFSH can be added to testosterone plus HCG improve fertility. Testosterone also appears to require conversion to estradiol to stimulate normal sexual function and decrease body fat in men, as shown by an experiment in which men 20 to 50 years old were treated with a gonadotropin-releasing hormone (GnRH) agonist to suppress testosterone and estradiol secretion and then replaced with testosterone, with or without an aromatase inhibitor . Symptoms were low energy, So, only one week ago, I started hCG monotherapy at a dose of 350IU EOD, which is a moderately low dose from what I’m told. Hsieh, T. 5 years that I was on it, I usually measured around 1100 total testosterone, except for two instances where I pulled a 1496 and a >1500 during those 2. testosterone, and impairs spermatogenesis, leading to azoospermia in 40% of patients. 135 Meadowlands Pkwy, Secaucus, NJ 07094. Both cases had a live birth. This is one of if not the most commonly used testosterones in Testosterone Replacement Therapy (TRT). My e2 was quite high w my T dose, so I increased my AI by . If you check the studies, some people are very reacting a lot to HCG and need a low dose, other people start reacting only at higher doses like 500 iu EOD or even more, but on trt I think 500 iu EOD is the maximum. Patients should be appropriately pretreated with human menotropins. Knowing how many factors can affect the levels of testosterone, Therefore you may only need a lower dose of testosterone if you are also taking HCG on TRT. Doses of HCG as low as 400 IU seem to significantly increase serum testosterone levels and even with dosages, 10 times that amount (4000 IU), the serum testosterone elevations seem similar to that of a 400 IU dosage (i. Patients and methods: A total of 282 men with hypogonadism, wishing to preserve their fertility, were randomized to one of three Effect of Combined Low Dose hCG, FSH and Testosterone therapy versus Conventional High Dose hCG and FSH on Spermatogenesis and Biomarkers in Men. In a retrospective study of boys with CHH, treatment with 5,000 in weekly hCG injections and monthly I inject 18 mg of testosterone cypionate daily and 500 IU of HCG twice a week. , et al. It’s crucial In male congenital hypogonadotropic hypogonadism (CHH), it was observed that lower dose human gonadotropic hormone (hCG) can maintain normal intratesticular testosterone levels. A previous study has demonstrated that hCG taken every other day preserved spermatogenesis in men on 250IU x2 per week is a very conservative hcg dose, when I first started TRT my estrogen levels were very low, but as my testosterone raised significantly my estrogen crept up and went shooting through the ceiling. This study indicates that low-dose hCG is able to maintain endogenous testosterone production within the normal range in men with gonadotropin suppression. We propose this study to compare the low-dose hCG, follicle stimulating hormone (FSH), and Testosterone (T) [LFT Regimen] to conventional treatment to induce virilization and fertility. hCG can help the body increase its production of testosterone and There is some evidence that hCG treatment can increase testosterone levels. Control estrogen and take low dose trt like 80mg trt with 300iu three times week Hcg. As for hCG as you can see from the post it's between 60 - 150iu for their daily dose. Also many people are different, some use 500ui and never experience shrinkage, I use 1,000 and definately noticed shrinkage in the first month but that could also be driven by sex drive going through the roof and nutting alot more frequently (average twice per day, 3 or 4 times on Why Testosterone Replacement with HCG is a must to ensure long term postive results. I also didn't care about atrophy, because balls are overrated anyhow, lol. Many of our hormones act in a cascading event and the axis between the these three glands are no However, the hCG dose is very high and seems like it would drive up estrogen quite a bit. Testosterone is a fundamental hormone to optimal physiology, HCG can be given in 2 ways: high dose or low dose: Low Dose HCG. It does not aid in secretion at the pituitary. Crisler. I'm not a low shbg guy. 2%) unknown types of testosterone), who were given 3000 units of HCG every other day after termination of When used in small doses 2-3 times per week along with testosterone replacement, HCG can reverse the decrease of intratesticular testosterone. COMBINED CLOMIPHENE AND LOW-DOSE KYZATREX (ORAL TESTOSTERONE) THERAPY IN HYPOGONADAL MEN: A CASE SERIE Nelson Vergel; Dec 17, 2024; Replies 3 Views 206. The following article has a good review of indications for BhCG in men. Feel amazing after adding low dose HCG? Ive been prescribed TRT for about 4 years now and just recently added low dose HCG (250 mg every 3 days) and wow I feel incredible. e. Testosterone Cypionate doses can vary greatly depending on the purpose of use and the desires at hand. It's debated all over HRT forums how much weekly HCG one should get. , remaining within the physiological range). What’s the best age to start TRT? There’s no “best” age to start TRT, but it’s generally more common among * Total testosterone has lower sensitivity for hypogonadism in men aged > 50 years. Dec 29, 2024. Therapies that protect the testis involve human chorionic gonadotropin (hCG) therapy or selective estrogen receptor modulators (SERMs), but may also include low dose hCG with exogenous testosterone. With this background, we postulated If you take a low dose of HCG, your T peaks 4 days after injecting, and drops back to normal quite quickly. In this review, based on a literature review for the years 1977-2020 via Google Scholar, we summarize the current research on HCG as treatment for patients suffering from low testosterone and provide an overview of the pros and contras for HCG therapy as compared to testosterone replacement therapy for the treatment of secondary hypogonadism. c. Our patient's testosterone level normalised 3 months after starting HCG therapy, and an appreciable spermatogenesis was observed at 9 and 12 months (combination therapy started at month 5). Jarow, Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Testosterone Replacement, Low T, HCG, & Beyond "How to" Guides . This is true in both your pre-TRT low testosterone state, as with introduction of exogenous testosterone and HCG, and with healthy hormone levels. I think I will be jumping back on HCG myself. Figure 7 Maintenance of ITT levels with hCG and IM-TC. This subreddit is for questions and discussion related to testosterone replacement therapy and testosterone. HCG is best taken in smaller doses more frequently. 40 ml IM/SQ 2x a week and just added HCG 500 iu 2x a week into my regime. We evaluated patient age, treatment indication, hCG dosage, past medical history, physical exam findings and serum testosterone and gonadotropins Human chorionic gonadotropin is primarily known for it’s production during human pregnancy by the developing embryo after conception, and later followed by syncytiotrophoblasts in the placenta. If the test for free and weakly bound follicle-stimulating hormone (FSH). And I’ve never taken HCG. For a low shbg guy. 5 years. As a medication, HCG (Pregnyl, Novarel) is used for fertility treatments in females. r-HCG should not be given until adequate follicular development is indicated with serum estradiol and vaginal ultrasonography; treatment should be withheld in patients with excessive ovarian response (e. The use of exogenous androgens can influence the HPG axis by similar mechanisms as endogenous testosterone by exerting negative feedback in a dose- and duration-dependent fashion, resulting in reductions in ITT, blunting of FSH production, and ultimately decrease or complete cessation of spermatogenesis. My hcg dosage is 1,000ui per week and costs £35- for 5,000ui shocking prices your being charged. Thankfully that really helped, along with switching to daily injections. Noonan syndrome may occur sporadically or as an autosomal dominant disorder. Welcome to ExcelMale. Keeps estrogen low and keeps some size in the balls. hCG is generally only produced by women during pregnancy, but it is an analog of luteinizing hormone (LH), which is produced H in luteal-phase stimulation in the presence of endogenous or exogenous low-dose hCG. Thread starter Nelson water so that they can dilute the HCG down to a more workable concentration that is more practical for men using lower doses of HCG weekly. Thread We propose this study to compare the Low-Dose hCG, follicle stimulating hormone(FSH), and Testosterone(T) [LFT Regimen] to conventional treatment to induce Sounds like it could be an E2 spike from the hcg. I would suggest lowering the interval to every two days and increasing the dosage until you feel they are least aren't shrinking anymore. Low-dose testosterone is now an increasingly popular choice for hypogonadal men with low testosterone. 123,124 Measurement of intratesticular testosterone showed that hCG treatment at relatively low doses was able to maintain intratesticular testosterone concentration when gonadotropins were suppressed I'm also on 500 iu EOD of HCG while on trt, because 250 iu eod didn't work a lot for me So same situation here. Testosterone medication options. However, when comparing the lowest hCG dose in that study, 125 IU every other day, to the group receiving gonadotropin suppression alone, the 17-OHP concentration was the same. These results demonstrate that relatively low dose hCG maintains ITT within Figure 2: Even low dose HCG improves Serum T levels. Effects of low-dose testosterone undecanoate treatment on bone mineral density and bone turnover markers in elderly male osteoporosis with low serum Gonadotropin levels are high with low testosterone levels. You'll be fine and you'll save money as well. The most effective dose of hCG to preserve fertility while on TRT varies, but several studies provide guidance on dosing strategies that balance efficacy with minimizing potential side effects: 1. hCG stimulates the Leydig cells in the testis to produce testosterone in hypogonadotropic Weekly treatment with hCG appears safe and can improve hypogonadal symptoms in patients with T >300 ng/dl without changes to hematocrit, prostate-specific antigen, and hemoglobin In men, doctors prescribe hCG to help address the symptoms of hypogonadism, such as low testosterone and infertility. Mar 14, 2018 Testosterone Replacement, Low T, HCG, & Beyond. What the commercials don’t tell you. Objective: In male congenital hypogonadotropic hypogonadism (CHH), it was observed that lower dose human gonadotropic hormone (hCG) can maintain normal intratesticular testosterone levels. hCG mimics LH analog. mood is up, energy is high and anxiety down. 5-9 In addition to larger testicular volumes, prior exposure to gonadotropins was also linked to a favorable response to fertility treatments Recently had suspicions about having low testosterone and possibly being clinically hypogonadal. Although immunoreactive LH and bioactive LH concentrations are related, differences are often observed. Howdy, I’m getting my first round of labs done since starting trt and HCG 5 weeks ago. S. Once I was over 35, I wrote off PCT forever and went on TRT. Doses of HCG and testosterone should therefore be adjusted accordingly based on follow up blood test results. Off-label use of SERMs, such as clomiphene citrate, are effective for maintaining testosterone production long-term and offer the convenience of representing a safe, oral therapy. Even with an elevated dose (as high at 3000 IU TIW, which caused remarkable, unsustainable aromatization) I wasn't feeling good. Clomiphene is not effective enough when you're Hypothalamus and pituitary are suppressed from exogenous testosterone (counterproductive). Testosterone Replacement, Low T, HCG, & Beyond. co. Marietta, Georgia, 30060. I’m 2 doses in on the HCG and so far no noticeable change in how I feel. Azoospermia develops in up to 40% of patients on TRT, but co-administration of low-dose HCG can maintain intratesticular testosterone and preserve spermatogenesis. HCG is given as an injection under the skin or intramuscularly I know adding HCG to my regimen upped my total Testosterone to high at 1200 range, so we dropped my dosages: T from 80mg to 70mg HCG from 650 IU to 500 IU and that put my T in about my ideal 900 range and T:E2 ratio is also in a great range. I've reduced my dose of T and stopped the rest. However, the minimal dose of hCG needed The papers you provided prove one thing: Estradiol shouldn't be tanked, and testosterone should be higher than the low end of the reference range, to best foster libido, except in these rarer cases of needing to tank estradiol to stop cell proliferation in the pituitary lactotropes. So, the lowest dose of HCG is zero. Steve78. All participants also received 500 IU hCG every 2 days. I wound up on this dose because there is supposed to be a period of time at even higher doses to reverse atrophy (or cause hypertrophy) of 4,000iu 3/wk for 2-6 months. It’s used in women to help treat infertility but it’s also used in men with hypogonadism (“low-T”). T: +44 (0)1202 091593; info@themenshealthclinic. I just started my HRT program about 3 weeks ago and I'm curious if my HCG dose levels are 'normal' or high? Free test: ~ 55 ng/dL Total test: 175 ng/dL Test cyp: 100mg every 3-4 days HCG: 600iu every 3-4 days 1200iu just seems like a shitload Just like taking test cyp every third week also makes for very low numbers towards the next injection. For men who suffer from low testosterone, hCG (human chorionic gonadotropin) may be recommended alone or in combination with testosterone to attempt to preserve fertility and prevent testicular atrophy. IMO 250-500iu EOD is plenty. 12, 13 In this context, developing a regimen with an optimal dose of hCG sufficient to cause This subreddit is for questions and discussion related to testosterone replacement therapy and testosterone. How many years did you take hcg and testosterone before stopping hcg? Reply reply More replies [deleted] They had fallen back in / retracted like a prepubescent nine year old. Eventually trt is the answer but I might try and see if this can be successful first or try hcg mono therapy for a bit. The most common dose-limiting side effect of exogenous T is increased or T) concurrently with hCG or did not have a follow-up testosterone laboratory result after at least one month patients reported erectile dysfunction, low libido, and low energy at the time of presentation to the clinic. As a result of the above, around 1000 units per week split into divided doses is a suitable starting point for retaining normal ITT. I dose Testosterone Sunday/Thursday, 100mg/week. It is known that pERK1/2 activation supports both steroidogenic signals and GPCR downregulation , however, the levels of Erk1/2 and Creb phosphorylation induced by low LH/hCG doses (i. 7%) used injectable testosterone, 16 (32. An idiosyncratic side effect of hCG might be an allergic reaction—rare, but it happens. Brown, Xiaohua Yan, Barry R. A low dose of BhCG is typically 500-1500IU weekly according to the literature, which I split into three to four doses weekly. now if your actually cycling and coming off inbetween cycles HCG works amazingly well taken at a low dose DURING the cycle not after. Anxiously waiting for lab results to come in, but think I am going to cut the HCG dose in half (125 IU 3x/week = 375 IU a week total. Since low testosterone levels have the potential to affect libido and impact sexual function, it is possible that hCG can help with erectile dysfunction. A Few month ago I was above 300 now my TT is below 300 and my Free T is still low also. I think a good starting daily dose is between 10 mg - 16 mg of testosterone and 100 IU of HCG. Taking HCG can keep this from happening. Posttreatment ITT was 25% less than baseline in the 125 IU hCG group, 7% less than baseline in the 250 IU hCG group, and 26% greater than baseline in the 500 IU hCG group. HCG is oftentimes used in TRT- Testosterone Replacement Therapy to raise the levels of the intra-testicular testosterone hormone which drops during the treatment. A systematic review showed that hypogonadal men desiring fertility preservation while benefiting from TRT can be prescribed SERMs or testosterone plus a low dose of hCG. The Leydig desensitization issue probably isn't real, but there are other issues with taking too much. Prescription of hCG alone or in combination with FSH preparations can be recommended to hypogonadotropic hypogonadal patients who need to be treated for infertility ( 46 ). Vitamin D and testosterone are two of the most important factors in our health but are often overloo I used HCG many years ago when on cycle, or toward the end of a cycle as a PCT primer. We propose this study to compare the low The use of HCG alongside testosterone is supported by the American Urological Association 12 and its role in maintaining fertility whilst Terry R. Thank you. It's also very similar to luteinizing hormone (LH), a hormone involved in reproduction in males and females. Full balls, decent libido, Previous studies on pubertal induction using hCG monotherapy and hCG + rFSH have each shown testicular growth and spermatogenesis in addition to adequate virilizing effects and better quality of life when compared to testosterone alone. Remember that when you use hCG you emulate luteinizing hormone thus stimulating the testicles to produce testosterone endogenously. According to research , hCG restores fertility in up to 70% of patients with hypogonadotropic hypogonadism (i. 56 These data are supported by the finding from I haven’t tried to see what hcg dose maximizes my testosterone. Which I would have done whether starting the HCG or not. , in another study, confirmed that intra-testicular testosterone could be maintained during testosterone At this point I'm thinking about doing low dose T + hCG + super low dose Ai. We performed a multi-institutional retrospective case series of men receiving hCG monotherapy for symptomatic hypogonadism. JClEndoMet 2005]. After about three years, though, I saw diminishing returns. Get bloodwork done and gauge your levels accordingly. Descriptive NEW ORLEANS — Low-dose human chorionic gonadotropin, or hCG, may preserve spermatogenesis in men with hypogonadism treated with intramuscular or Current guidelines recommend TRT for men with two T levels <300 ng/dl and symptoms of low T. I'm curious what others are taking for their weekly injections for testosterone and HCG. In one protocol, a one-time dose of hCG 100 units/kg IM is given. 25mg anastrozole every few days, and took 20mg nolva for a week to blast some gyno i was developing. One small study examined the clinical charts of 37 male subjects who presented with low libido, low energy, erectile dysfunction, and insomnia—all symptoms of hypogonadism, (the medical term for Low T), but who had a serum testosterone level greater than 300ng/DL, one measurement used to diagnose low testosterone. 25mg aromasin twice a week to control it. The third case had 7 repeated In this setting, short-term, low-dose testosterone therapy should be withdrawn to determine whether spontaneous puberty is occurring. HCG’s effect as a LH mimicker plus its ability to increase IT seem to be the reasons why men were able to preserve fertility (normal sperm) when using testosterone replacement plus 500 IU HCG every Relatively low testosterone was defined as testosterone <15 nmol/L in combination with, (1) low free testosterone <243 pmol/L or (2) young adult males with a history of orchiectomy and clear complaints of hypogonadism. HCG greatly stimulates aromatization in Leydig cells, so estradiol can easily get to be a problem. This subreddit is for questions and discussion related to testosterone replacement therapy and as in my case hcg raises E2 to the point is itching my nipples even at low doses Butt totally restored volume load and, to some extent, very low dose HCG got my wife pregnant 250 IU 3x per week along with 150mg Test Cyp, but feel like my E2 is high considering I got gyno, acne, and low libido 2 months after starting TRT/HCG protocol (still trying to get dialed in). Learn More About The Free Consultation. It is also one of the most commonly used in performance settings second only to Testosterone Enanthate. A 2018 study investigated the effect of hCG on testosterone levels in 20 males with one or more of the following symptoms In this review, based on a literature review for the years 1977-2020 via Google Scholar, we summarize the current research on HCG as treatment for patients suffering from low We evaluated patient age, treatment indication, hCG dosage, past medical history, physical exam findings and serum testosterone and gonadotropins before and after therapy. This approach involves using HCG at a lower dose alongside exogenous testosterone. After this period is over, it’s been found that this treatment has effectively boosted testosterone levels in a majority of these men by 60%. com, The main reason to add hcg to testosterone is for fertility/cosmetic purposes as hcg (human chorionic gonadotropin) mimicks lh and seeing as lh is shutdown when using exogenous testosterone using hcg will mimic lh and stimulate the leydig cells in the testes to produce ITT (intra-testicular testosterone) and to also prevent the testes from atrophy. I’ve been on trt for 6+ years, and my nuts haven’t shrunk. 125. You may need a low dose of a safe AI such as 6. It's a lot. uk; It therefore stands to reason that the normalisation of male androgen levels by use of small doses of both exogenous testosterone and HCG allows for the preservation of a level of fertility not available to those on monotherapy alone. I introduced a low dose of 100ui every day and found the sweet spot. Human chorionic gonadotropin works as an LH analogue stimulating leydig cells to produce testosterone in the testicles, a requirement for spermatogenesis (8). hCG stimulates Leydig cells, as does LH, with which it shares a structural subunit, and stimulates testicular production of testosterone. **Low-Dose hCG**: A common approach involves the administration of low-dose hCG to maintain intratesticular testosterone levels. Of note, not all subjects in the Hypogonadal groups exceeded the lower limit of normal for the response of serum testosterone concentration at each one of the three doses of hCG: at the 400 IU In a study of normal men treated with TRT and randomized to concurrent administration of placebo or low-dose hCG (125, 150 or 500 IU) every other day, ITT levels were maintained in all hCG groups with levels closest to baseline normal in the 250 and 500 IU dose groups, thereby suggesting preservation of spermatogenesis. I’m on my first week of HCG 200iu Should I lower my testosterone dose to account for the increase due to HCG. It's also used in certain cases to raise testosterone levels in males and One retrospective study on the effects of HCG therapy on the recovery of spermatogenesis after testosterone recruited 49 men (16 (32. In a study published in the Journal of Clinical Endocrinology and Metabolism , even a low dose of hCG with TRT helped to keep intratesticular testosterone levels at a normal range. Ask a male who is on TRT (Testosterone replacement therapy) due to low Testosterone production the same question, and you might get a completely different answer. Smals AG, As a result, testosterone levels increase, which is the primary objective of a low testosterone patient. Theoretically this isn’t much different than trt with hcg but I’m curious to try to keep my pituitary working. I have always used HGC as per Dr. However, intratesticular testosterone can be maintained during testosterone replacement therapy with co-administration of low dose human chorionic gonadotropin, which may support high-dose hCG will normalize plasma total T levels, few studies have reported that long-term usage of high-dose hCG can have a detrimental effect on testicular functioning. Intratesticular testosterone levels were suppressed by 94% in the placebo group, 25% in the 125 IU hCG treatment group, and 7% in the 250 IU hCG treatment group, and they were increased 26% from baseline in the 500 IU hCG This subreddit is for questions and discussion related to testosterone replacement therapy and testosterone. How to maintain fertility on TRT (testosterone replacement therapy)? Is low dose HCG enough to preserve fertility (sperm production) on steroids or TRT? W hCG and TRT (Testosterone Replacement Therapy) for Men — hCG and Fertility. Testosterone is high, estrogen is in proportion; however, still have low libido & low mood. A starting dose of testosterone is closer to Testosterone deficiency (TD), or male hypogonadism, is a clinical syndrome that can be defined as persistently low serum testosterone levels in the setting of symptoms consistent with TD. CC was used in combination with TTh, human chorionic gonadotrophin (hCG) or aromatase inhibitors (AI) After a number of years if men stop taking TRT their native production of testosterone, albeit low in the first place, might not return. I have read a few studies suggesting that tamoxifen citrate (Nolvadex) may have a synergistic effect in increasing testosterone in the case of long-term HCG monotherapy as it can block desensitization of the leydig cells (example: Tamoxifen suppresses gonadotropin-induced 17 alpha-hydroxyprogesterone accumulation in normal men. Researchers measured serum hormone levels of free testosterone and estradiol and semen parameters before and during treatment. 1 Uses and Benefits of HCG with Testosterone in Men. Just remember, appropriate hcg doses are key! This boost from hcg use can be particularly beneficial during post cycle therapy (PCT), where hormonal balance is key, especially for those with low testosterone. Since discontinuing hCG, my testosterone levels have been right around 1,000. Injecting 12. Estradiol: The Estrogen Effect. Especially on such a low dose. HCG Dosage Calculator. But hCG might crank Previous studies on pubertal induction using hCG monotherapy and hCG + rFSH have each shown testicular growth and spermatogenesis in addition to adequate virilizing effects and better quality of life when compared Microdosing testosterone is a tool for more subtle or slower changes at smaller doses. Both Gonadorelin and hCG can stir up some estrogen (estradiol) in guys. if you're going to take something, I'd much rather take, you know, um, a, a lower dose nandrolone or something along those lines just to mitigate the side effects tremendously. daily. Previously we found that lower dosages of hCG stimulated IT-T to normal. Doses of 2000IU every other day are needed to increase testosterone into the mid-range (500-600ng/dl) and 4000IU daily is needed to increase testosterone into the upper range (1000ng/dl). In addition, after peak testosterone production, higher doses of hCG actually cause reduced production and lower levels. Personally, I'm currently using 1500 units per week of HCG in three divided doses plus HMG (menotropin) 150/150 units on alternate days, as a source of FSH. NEW ORLEANS — Low-dose human chorionic gonadotropin, or hCG, may preserve spermatogenesis in men with hypogonadism treated with intramuscular or transdermal testosterone replacement therapy For many men with symptoms of low testosterone, HCG is a useful add-on for their program. If you take a higher dose, your T peaks at 4 days, and stays at that peak level for longer. When i upped the dose and introduced hcg, I started getting some high estrogen signs. Diagnoses: Patients were diagnosed with infertility. I have aromisin now but don't use, Hcg gives me brain fog headaches and anxiety and can't sleep. In the 2. 2%) a combination of the three, and 4 (8. Do I need hCG if I’m already on testosterone? It really depends. During therapy, his PSA levels went above the normal range, but normalised after stopping and restarting HCG at a lower dose (1500 IU a week). hCG is a naturally occurring hormone. Despite clinical doses of exogenous testosterone, low-dose hCG can maintain high levels of ITT. You won’t need hCG to raise your testosterone levels because we’ll give you an adequate dose to get you to optimal levels. Reply. 7%) transdermal testosterone, 7 (14. “the pregnancy hormone” found in urine on a pregnancy test, is actually HCG! Additio The initial dose of hCG 1000 - 1500 IU (40 - 60 mcg) s. Studies have shown that low dose HCG (500 IU SQ 3 times per week) was adequate to maintain normal intratesticular levels of testosterone. I didn't worry about HCG, because I didn't want children. , that a relatively low dose of hCG maintains ITT within the normal range in healthy men with gonadotropin suppression due to testosterone supplementation. These results demonstrate that relatively low dose hCG maintains ITT within the normal range in healthy men with gonadotropin suppression. But I have a friend that tells me the following, "HCG looks great on paper but if your TRT for life its a complete waste, you will notice zero difference, been there done that. He keeps pushing clomid if I want fertility. I'm secondary, and fertility is a major concern for me. Some people tolerate HCG well, others like myself included do not. I use an easy touch 29 g half inch syringe. Understand its benefits, dosage, and how it can help with fertility and hormonal balance. , significant ovarian Low testosterone levels alone do not require treatment unless they are associated If LH levels are normal or low, clomiphene, hCG, Wang Y, Liu Y, Wang S, Tan P, Tang ZY, Liu YS. HCG is self administered as an injection into the subcutaneous fat, similar to insulin, with a tiny needle. In a 2013 study, researchers gave testosterone injections to 19 men with low T and transdermal testosterone gel to 7 men with low T. My doctor says that a low dose of testosterone which helps me reach a levels of 600 to 800 ng/dl will not result in testicular atrophy, and will not stop the body’s own production of Testosterone. Start lower with the HCG at first, say 250 iu twice a week. We have both gone down the testosterone route, testosterone Plus hcg, plus other options like clomid and etc. I do see guys on between 500-1500 units per week though. Low doses of hCG in conjunction with TRT may maintain testicular-produced testosterone and deter issues with testicular shrinkage. A low testosterone assessment conducted by doctors will involve blood tests taken weeks apart from each other to ensure your testosterone readings are Typically, the starting HCG dose is between 250 and 500 IU. Now I do 25mg of test, with the 100iu of hcg daily and haven't taken AI in a bit. But I have heard different things before, HCG is used in men on TRT to treat testicular atrophy and for fertility reasons, In addition to exogenous testosterone monotherapy, a number of other regimens have been used to treat low testosterone in these men, including AI monotherapy, hCG monotherapy, SERM monotherapy, and various combinations of these classes of drugs. 337-339 Patients with KS frequently have low levels of testosterone production and high levels of aromatase activity, However, low-dose HCG injections are effective at increasing intra-testicular testosterone, which is needed for sperm production. And as suggested, my labs are scheduled Thursday morning, prior to pinning. Edit: For me the hCG dose generates negligible endogenous Figure 1 – Approximate daily release of Testosterone using Nebido at 1000mg every 12 weeks. hCG during T therapy for the betterment of your health is wise. 29 Data specifically describing the natural In addition, 50–200 IU low-dose hCG or 75–225 IU rLH should prove useful for maintaining appropriate blood LH levels from the mid-follicular phase (day 6 of stimulation) of the GnRH antagonist proto-col. wolf359 October 29 Also, it has been concluded by Coviello, A. Home; About Us; Services. Testosterone replacement therapy (TRT) Doses of hCG Testosterone gel relieves the symptoms of low testosterone, restores sexual contraceptive studies 122 and in men after androgen abuse. 25ML x 2 daily and I like it better than the injections. It will balance every thing. The hCG dose is to be titrated based on testosterone levels, whereas the FSH dose is usually adjusted based on clinical signs . I have good insurance and am buying extra from India to take 2000iu daily. I took . Hsieh and Lipshultz demonstrated that low dose hCG (500 IU every other day) appears to maintain semen parameters in hypogonadal men on topical or intramuscular testosterone therapy . Both myself and my brother have dealt with low testosterone for the past 10 years. In 2014, I began taking a low dose of hormones to achieve subtle masculinizing effects, a process that I call microdosing testosterone (or “T”). D. The introduction of hCG into the treatment regimen can help counteract this effect, maintaining intratesticular testosterone levels, which is crucial for preserving fertility and avoiding testicular shrinkage. It's better to control estrogen via smaller, more frequent testosterone doses and minimum effective HCG doses first. Indications for the use of human chorionic gonadotropic hormone for the management of infertility in hypogonadal men That was anastrazol. Testosterone Basics & Questions . Human chorionic gonadotropin (hCG) is a hormone that's naturally made in the body during pregnancy. C. Increasing doses of hCG may reduce testicular stimulation by down-regulating the end-organ; thus, a more optimal result may occur with less frequent or reduced dosing. How much does HCG raise testosterone? I’ve come across a post Hello, I’m currently on 120mg Test C split into 40mg MWF. hCG generally impacted my total testosterone level by 100 on 500 iU of hCG administered 2x per week. A challenging patient population are men with symptoms of low T who do In TRT, it refers to administering smaller doses of testosterone more regularly to achieve normal blood testosterone levels without the peaks and troughs in levels that you get from injecting less regularly. Before I added test in May 2021, my test even with HCG (1000 IU TIW was my last monotherapy regime) my testosterone was an insanely low 127. converts to e2 and levels spike - even if you then decrease your testosterone dose, the e2 levels take longer to decrease Everyone is different but there is absolutely Another treatment used is human chorionic gonadotropin (hCG) injection monotherapy. We were trying to get my estrogen close to 150, Without hCG: Total testosterone per week—67 mg Estradiol: 57 pg/mL With 1,050 IU hCG per week: Total testosterone per week—43 mg Estradiol: 57 pg/mL That's right, for me 1,050 IU per week of hCG creates as much additional estradiol as a 56% increase in the dose of testosterone. Tons of studies on HCG, tons of guys who report feeling great on HCG solo but obsess over serum numbers and think the HCG isn't working well enough. Alright, I've got an idea. Ongoing hCG administration at a dose of 250 IU EOD—blast or cruise, rain or shine, will keep Leydig cells operational, preventing the deterioration and oxidation damage of long-term dormancy. 9 Other studies have shown that long-term high-dose hCG produces inflammatory changes in the testis, leading to germ cell apoptosis. I need to Context and Objective: In men with infertility secondary to gonadotropin deficiency, treatment with relatively high dosages of human chorionic gonadotropin (hCG) stimulates intratesticular testosterone (IT-T) biosynthesis and spermatogenesis. Of the patients reporting these In male congenital hypogonadotropic hypogonadism (CHH), it was observed that lower dose human gonadotropic hormone (hCG) can maintain normal intratesticular testosterone levels. Often when we increase our testosterone dose, we initially feel amazing until the test. Low Testosterone Check Contact & Book. We have each worked with different urologists as we live in different cities and different treatment clinics to assist us with our hormone therapy. Some atrophy is to be expected on TRT though, even with HCG. In secondary hypogonadism (hypogonadotropic hypogonadism), defects in the hypothalamus or pituitary result in low testosterone levels because of In one published study, medical professionals administered hCG injections over a span of 6 months at a dosage of an average weekly hCG dose of 2000 IU in men with low testosterone. With HCG, your T levels aren't dose dependent, but how long that your levels stay that high is dose dependent. My question is how much of an increase in T and E2 can I expect from hCG? I am planning on a lower dose, either 200 - 250 IU/day or 400-500 EOD, just to keep intratesticular testosterone higher and keep Leydig cells If it's 100mg weekly that's ~14mg/day of testosterone injected. By administering hCG along with exogenous testosterone, this will keep natural testosterone production going. Reply reply A normal dose for hCG monotherapy is 2000-2500 3/week. However, intratesticular testosterone can be maintained during testosterone replacement therapy with co-administration of low dose human chorionic gonadotropin, which may support continued spermatogenesis in patients on testosterone replacement therapy. is given three times a week. 12,13 On the other hand, exogenous T will not impair sperm production in HH as the HPT axis of these patients is already nonfunctional. HCG can also help maintain fertility during TRT. Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression Testosterone Cypionate Doses. 3%) pellets, 6 (12. HCG or Human Chorionic Gonadotropin is a Low-Dose TRT: In some cases, a low dose of TRT might not significantly impact LH and FSH production, reducing the need for HCG. ABOUT US. So I’ve been on T for about 5 months, T Cyp 200 mg/ml – 0. To function optimal it can give you a range of 700 to 800 easily. Reply reply Posttreatment ITT was 25% less than baseline in the 125 IU hCG group, 7% less than baseline in the 250 IU hCG group, and 26% greater than baseline in the 500 IU hCG group. Outcomes: The first two cases had inadvertent COH during preexisting pregnancy, and one of which produced more high-quality embryos (5 vs 1) in the presence of low hCG. 866-349-5698. I just placed my order with TRT Nation, currently taking 200mg/week of testosterone enanthate, split between 3 injections each week, as well as 1000iu HCG per week in 3 sub q injections, I feel great physically and mentally, but sex drive isn’t exactly where I want it to be, but it is much MUCH better than it was, and I no longer have ED. I would like to know your opinions about what is the lowest effective dose of HCG . secondary hypogonadism – a failure in the hypothalamus or pituitary gland). Therefore, it seems possible that serum 17-OHP correlates with IT-T in the presence of normal or near-normal hCG stimulation but not with low-dose hCG stimulation. Feel amazing after adding low dose HCG? Thread starter Arcane; Start date Jun 4, 2022; Tags hcg 1; 2; 3; Next. Book a Consultation. While improvement in symptoms was not the primary outcome study of this investigation, the use of HCG to raise testosterone levels was evident. This put me at TT 1100 (240 - 950) and FT 44 (9 - 30). Dr Justin Saya MD Moderator. Learn about the optimal weekly amount of HCG for boosting testosterone levels. Zirkin, Jonathan P. Some experts recommended HCG doses of 10,000 units. This information has been complied by: gdevine When a man introduces Testosterone exogenously it significantly changes how the Hypothalamus(H), Pituitary(P) and Testicle(T) glands react to each other in keeping men's androgenic hormones in balance. 10 1 and 10 2 pM) are close to the detection limits, not allowing to reliably address why gonadotropin treatments result in equal pCreb activation in the entire dose-range. It also focuses on lifestyle activities like exercise and nutrition for raising testosterone levels naturally or anything else related to testosterone the substance. Understanding the Balance The decision to include HCG in your TRT regimen I mentioned HCG with testosterone and he knew nothing of using it or how to even dose it. As we can see, there are large swings in the daily release over time, with the C min becoming quite low indeed further into the year. wmqufa xwnu ivjq wjj morllzt ufjb kxgesah isctk pukxdw copgo